Reuben Houston Burrow (December 11, 1855 – October 9, 1890), better known as Rube Burrow, was an infamous train-robber and outlaw in the Southern and Southwestern United States. During the final years of the American frontier, he became one of the most infamous and hunted men in the Old West since Jesse James. From 1886 to 1890, he and his gang robbed express trains in Alabama, Arkansas, Louisiana, the Indian Territory and Texas while pursued by hundreds of lawmen throughout the southern half of the United States, including the Pinkerton National Detective Agency.

Born in Lamar County, Alabama on December 11, 1855, Rube Burrow worked on the family farm in Alabama until the age of 18 when he moved to Stephenville, Texas to work on his uncle's ranch. By all accounts, Burrow fully intended to become a rancher by saving up enough money to buy a farm, marry and start a family. He attempted farming but his wife died of yellow fever in 1880, leaving him to care for two small children. He remarried in 1884 and moved to Alexander, Texas, but when his crops failed he turned to robbing trains with his brother Jim in 1886.